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The requirement for vitamin D (15 micrograms/day or 600 IU/day) is not increased during pregnancy, but vitamin D is considered a shortfall nutrient in the diet and low vitamin D status (less than 50 nmol/L [20 ng/mL]) is common in pregnant individuals

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The differentiation of MSCs toward the osteogenic lineage is tightly controlled by different molecular factors, including the bone morphogenic proteins (BMPs) [95, 96], and wingless-related integration site (WNT) pathway [97, 98]
