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We summarize mechanistic insights across cellular and molecular domains, critically appraise preclinical and clinical findings, and discuss translational challenges that include bioavailability and brain penetration, study heterogeneity, biomarker guided stratification, and pediatric safety

PMID: 30636774

CircIL4R positively regulates the expression of GPX4 by adsorbing miR-541-3p, facilitates tumorigenesis, and inhibits ferroptosis in HCC cells (Xu et al., 2020)

Thus, TrkB and Akt are likely required for BDNF- and GSB-106-stimulated BAD activation in serum withdrawn SH-SY5Y cells