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A 2025 review published in the International Journal of Molecular Sciences at the Medical University of Warsaw documented five distinct biological pathways the peptide activates

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Furthermore, emerging evidence reveals that circadian misalignment promotes metastasis by enhancing tumor stemness and modifying the tumor immune microenvironment, while also impairing the efficacy of cancer therapies such as cisplatin 57,58

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However, it is important to keep the evidence in context