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This response can include widespread inflammation, allergic reactions , migraines, digestive issues, skin irritations such as eczema and acne, bloating, chronic fatigue, rheumatoid arthritis, hormone imbalances, autism, fibromyalgia and more

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10.1038/s41586-019-1170-y 410 WangW.LuZ.WangM.LiuZ.WuB.YangC.et al (2022c)

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In conclusion, the results collected from this study demonstrate that the copper treatment can induce heart rate irregularity in zebrafish embryos, and this adverse effect can be nicely rescued by administrating recombinant GHK tripeptide