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synthesized quercetin in actinomycete organisms ( Streptomyces coelicolor and Streptomyces albus ) using heterologous expression of their plant biosynthetic gene pathways
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obesity : excess fatty foods, which can increase levels of oxidative stress

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However, studies have proposed NO to represent a double-edged sword with its overproduction leading to a multitude of NO by-products implicated in mutational events and carcinogenesis
