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These individuals suffer from a disorder called Tangier disease which is characterized by two clinical hallmarks

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10.1038/nature22369 Nature 147 van DierendonckX.de la Rosa RodriguezM

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This is the practical way to avoid undersized or oversized systems later on

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BATES, Harold Eugene BATES, Tobert Alvin BATOR, Edward BATTLES, Ralph Curtis BAUER, Harold Walter BAUM, Earl Paul BAYS, Donald E

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10.1007/s00203-016-1291-8 157

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We further found that the melatonin receptor 1B (MTNR1B), rather than melatonin receptor 1 A (MTNR1A), is essential for MT mediated TRIP13 downregulation

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