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These individuals suffer from a disorder called Tangier disease which is characterized by two clinical hallmarks

10.1038/nature22369 Nature 147 van DierendonckX.de la Rosa RodriguezM

This is the practical way to avoid undersized or oversized systems later on
BATES, Harold Eugene BATES, Tobert Alvin BATOR, Edward BATTLES, Ralph Curtis BAUER, Harold Walter BAUM, Earl Paul BAYS, Donald E

10.1007/s00203-016-1291-8 157

We further found that the melatonin receptor 1B (MTNR1B), rather than melatonin receptor 1 A (MTNR1A), is essential for MT mediated TRIP13 downregulation
