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doi: 10.1016/s1734-1140(12)70933-7

[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Stromsnes K., Lagzdina R., Olaso-Gonzalez G., Gimeno-Mallench L., Gambini J

These phytochemicals principally interacted with pivotal neuro-inflammatory signaling waterfalls, improved brain enzymatic activity, decreased nitrosative stress and RNS formation, improved brain antioxidant defense, regulated of pro-inflammatory-related gene expression, restored the activity of astrocytes and microglial cells, modulated brain transcription factors expression, alleviated COXs expression, enhanced expression of anti-inflammatory genes, and protected brain neuronal cells (248, 401, 402)
It also showcased specific inhibitory effects against O-GalNAc in HEK 293T and Jurkat cells

A follow-up shot is required two to six months after the first, to ensure optimum protection
Although lactate was considered the villain in exercise physiology, recent research highlights its essential role in supporting cognitive processes, showing that it is crucial for optimal performance in tasks involving memory and executive functions [137]
