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designed iron oxide nanoparticles (IONPs), that can simultaneously deliver GPX4-targeting siRNA and cisplatin (Pt), a common clinical chemotherapeutic drug, to the GBM lesion region

For example, patients who are refractory to IMiDs have a higher frequency of cereblon mutations (210%) than untreated patients (0.5%)

There was no control group, no placebo arm, no blinding

A., Savovi J., Page M

Effects of shengmai injection add-on therapy to chemotherapy in patients with non-small cell lung cancer: a meta-analysis
Certain conditions such as kidney disease, heart failure, and some medication interactions may require physician approval or make IV therapy unsuitable
