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Back pain caused by intervertebral disc (IVD) degeneration is a chronic condition that profoundly impacts quality of life

[DOI] [PubMed] [Google Scholar] 89.Young M.J., Rickard A.J

That is an interesting hypothesis, not a validated protocol

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To focus on oxidative stress as a main damaging factor in an in vitro model is reasonable, as the diverse upstream causes for PN (hyperglycemia, dyslipidemia, some chemotherapeutics, alcohol abuse) converge into one prominent metabolic disturbance: the production of ROS and, thus, increased oxidative stress