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Description
Nrf2 is expressed the majority of cell types, where it is anchored in the cytosol by an inhibitory protein, Kelch-like ECH-associated protein (Keap1)
1996;271:C1424C1437
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In other words, all other antioxidants depend on this antioxidant to function properly
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One study suggests that the cholesterol-to-bile acid ratio is vital to supporting the homeostatic redox environment of HSCs [240]
