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Description
Necrotic apoptosis is followed by morphological changes such as rupture of cell membranes, translucent cytoplasm, swollen organelles, increased cell volume, and chromatin condensation

At 12 h after transfer, pancreas were collected and dissociated into single-cell suspensions as described above, and directly analyzed by flow cytometry to detect CFSE fluorescence in pancreatic cell suspensions
oxidative stress can disrupt lysosomes, releasing hydrolytic enzymes and iron into the cytosol, amplifying oxidative stress and ferroptosis (66, 78)

Sleep disturbance induces neuroinflammation and impairment of learning and memory
Clinical observations of patients have indicated that long-term exposure to high doses of propofol (surpassing 45 mgkg 1 h 1 and lasting over 48 h) can induce propofol infusion syndrome (PRIS) by damaging mitochondrial complexes II and IV in the muscles [30]

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