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Necrotic apoptosis is followed by morphological changes such as rupture of cell membranes, translucent cytoplasm, swollen organelles, increased cell volume, and chromatin condensation

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At 12 h after transfer, pancreas were collected and dissociated into single-cell suspensions as described above, and directly analyzed by flow cytometry to detect CFSE fluorescence in pancreatic cell suspensions

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oxidative stress can disrupt lysosomes, releasing hydrolytic enzymes and iron into the cytosol, amplifying oxidative stress and ferroptosis (66, 78)

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Sleep disturbance induces neuroinflammation and impairment of learning and memory

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Clinical observations of patients have indicated that long-term exposure to high doses of propofol (surpassing 45 mgkg 1 h 1 and lasting over 48 h) can induce propofol infusion syndrome (PRIS) by damaging mitochondrial complexes II and IV in the muscles [30]

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K.ChoN.ChoS

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