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Description
Extending these findings to metabolic health, we found that glucagon receptor signaling is indispensable to the metabolic response to chronic CR in young and aged mice

ATP production was measured over 72 min with the addition of 1.5 M Oligomycin at 24 min and 0.5 M Rotenone-Antimycin A at 48 min

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Parallel experiments on the guinea pig ileum confirmed that these peptides exerted strong opioid-like inhibitory effects on smooth muscle contractions, with relative potency trends similar to those observed in the behavioral assays
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