glutathione disulfide nov-002 Frontiers including the regulation of immune function and metabolism. Provoking tumor disulfidptosis by single-atom
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[PubMed] [Google Scholar] 115.Cen D, Brayton D, Shahandeh B, Meyskens FL, Farmer PJ

Sestrin regulation of TORC1: is sestrin a leucine sensor
Sortilin is modified by ectodomain shedding, although the biological implications of this are not known (Evans et al., 2011)

Iron-induced ROS production has emerged as another influential factor in the initiation of pyroptosis, and has specific mechanisms involving mitochondrial translocase of outer mitochondrial membrane 20 (TOMM20)-mediated CASP3 activation in melanoma cells [142]

Taken together, these works suggest that targeting the amino acid synthesis pathway may be another effective strategy for cancer therapy

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