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Moreover, it is worth to underline the need of exploring the role of iron-mediated oxidative damage through Fenton reaction to further ascertain the contribution of mitochondrial dysfunction and iron accumulation to the progression and pathologic development of age-related diseases

Many of these use donor-derived or commercially supplied exosome products, which are not currently licensed for injection by the MHRA

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One confounding factor is the complexity of antioxidants, referred to by Halliwell [6] as the antioxidant paradox, or the situation in which antioxidants such as glutathione can possess prooxidant activity causing a hormetic effect enabling the body to bolster its endogenous antioxidant defenses