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The Copper-Shuttle Hypothesis The single most cited mechanistic model for GHK-Cu is the copper-shuttle hypothesis

Pgp-positivity was revealed in 30-50% of acute myeloid leukemia cases (data of different studies), and this protein was more often found after courses of chemotherapy in the patients resistant to the treatment [34]

[DOI] [PubMed] [Google Scholar] Selected reviews:

Alterations of the skin and gut microbiome in psoriasis and psoriatic arthritis

Gene expression profiling of human decidual macrophages: evidence for immunosuppressive phenotype

Hodges RE, Minich DM (2015) Modulation of metabolic detoxification pathways using foods and food-derived components: A scientific review with clinical application