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Negative binomial regression models followed by post hoc comparisons of estimated marginal means using the emmeans 68 package in R with Tukey adjustment for multiple comparisons were used to evaluate significant differences in CR between stage 1, stage 2 and stage 3 in each of the following: CD incidence, UC incidence, CD prevalence and UC prevalence

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Furthermore, the expression of endothelial transcription factors within human brain organoids promotes neuronal maturation and reduces cell death ( Other studies have been based on the co-culture of human umbilical vein endothelial cells (HUVECs) with pluripotent stem cells before neural induction, which generated a vascular system formed by the HUVECs in the brain organoids, called HUVEC-BOs (Shi et al., 2020)