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In the human liver, -tocopherol is the form of vitamin E that is preferentially bound to -tocopherol transfer protein (-TTP) and incorporated into lipoproteins that transport -tocopherol in the blood for delivery to extrahepatic tissues

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Heavy metals in biological samples of cancer patients: A systematic literature review

They're placed at the ends to ensure no vital data gets left behind

NNMT inhibition doesn't directly affect gut motility, so prolonged GI symptoms suggest an individual sensitivity rather than a universal mechanism
