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examination, with attention to : Temperature: If there is any concern for possible hyperthermia, core temperature is ideal (e.g., rectal temperature)

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Indeed, it seems that the isomerization activity is catalyzed by a heme-free enzyme, whereas heme-bound mPGES-2s can degrade PGH 2 into hydroxyl heptadecatrienoic acid and malondialdehyde, instead of converting it to PGE 2 (Jania et al., 2009
