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Studies have demonstrated that specific strains of Bifidobacterium and Lactobacillus are pathogenic due to structural homology with the amino acid sequences of human TPO and Tg and thus can induce AITD through a cross-antigen-molecular mimicry mechanism (57)

For example, GPx1 has been reported to prevent oxidative DNA mutations, which in turn may prevent the development of tumors [42], and research shows that overexpression of GPx1 can reduce tumor growth, indicating its inhibitory effect in tumorigenesis [43]

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Contraindications and Special Precautions for Vitamin B12 Before taking vitamin B12 supplements, its important to know about certain warnings