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Cancers 11 , 675 (2019)
AACR Abstract 2019
Lack of renoprotective effects of targeting the endothelin A receptor and (or) sodium glucose transporter 2 in a mouse model of Type 2 diabetic kidney disease
In macrophages, the upregulation of 15-LOX expression catalyzes AA dioxide, leading to lipid peroxidation, which triggers ferroptosis in macrophages (51)
The Phase 2 type 2 diabetes trial evaluated retatrutide's glycemic effects alongside body-weight changes
