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The same study also demonstrated that perturbing glutamine pathway either via glutamine depletion or by using specific chemical inhibitors or due to genetic polymorphism (e.g., GLS2, SLC7A5, and SLC1A5), decreased T-cell associated cytokine production by the macrophages (PMID: 30541099)

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The central clinical concept is that DSIP is not a sedative

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They are mainly lipophilic anionic transporters and are reported to transport free or conjugates of glutathione (GSH), glucuronate, or sulphate

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Wu W, Ma J, Shao N, Shi Y, Liu R, Li W, et al

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