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The increased intracellular ATP consumption, increased tissue oxygen consumption and oxidative phosphorylation, overexpression of adrenergic receptors, and a decrease in antioxidant defensive mechanisms are the mechanisms of free radicals overproduction that favour OxS in hyperthyroid patients (46)

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Disorders where NAC or other nicotinamide-based treatments are commonly used as adjunctive therapies are often conditions in which sleep is taxed and tissue-level oxidative stress is high

10.1515/DMDI.2008.23.1-2.125 109 ToyodaY.ErkutC.Pan-MontojoF.BolandS.StewartM

Danik M, Jaishree P (2015) Nutraceuticals: the emerging therapeutic agents in health and disease

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