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Once a T-cell commits to a Th1 phenotype, it doesnt uncommit just because T1 is no longer present
Cornelius, M
Dual roles of p62/SQSTM1 in the injury and recovery phases of acetaminophen-induced liver injury in mice
doi: 10.1007/s00726-011-0864-8 64 HaoSYuJHeWHuangQZhaoYLiangBet al
However, such approaches are less likely to be useful clinically in of themselves due to lack of precisely-defined outcome measures and considerable overlap between disease groups
The present invention addresses these concerns
