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[DOI] [PMC free article] [PubMed] [Google Scholar] 298.Rajasekaran NS

This quick clearance limits the delivery of therapeutic payload over the long period of time for which the mucoadhesion is designed, reducing the bioavailability of inhaled therapeutics 145

pH Range: 4.5-7.0

This susceptibility of complex I to OS might be explicated by the oxidation of thiol (SH) groups of protein and the existence of accessible oxidation sensitive iron-sulfur centers in this complex [74]

While this process can be helpful early in life (like preventing cancer), too many of these cells in old age contribute to diseases such as heart problems, diabetes, and dementia