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In a systematic review, the median duration of cannabis use before the onset of CHS symptoms was 42 months and the median age of starting cannabis use in patients with CHS was 16 years.40 Duration of cannabis use was reported to be 1 year for 25.1%, 2-5 years for 36.3%, 6-10 years for 16.8%, and 11 years for 21.8% of patients
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2021 Mar;159(3):1076-1083

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Slow-twitch fibers (Type I) specialize in sustained, low-intensity contractions, and primarily rely on oxidative metabolism, while fast-twitch fibers (Type II) are optimized for rapid, powerful contractions, primarily fueled by glycolysis
Drug Chem Toxicol 45:11501157
