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Research to date highlights MOTS-cs ability to promote metabolic homeostasis (improving insulin sensitivity, encouraging fat utilization, and preventing diet-induced metabolic disorders) as well as its potential to mitigate aspects of aging (preserving muscle function, bone density, vascular health, and more)

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Vitamin B 12 deficiency, like folate deficiency, may lead to decreased synthesis of methionine and S-adenosylmethionine (SAM), thereby adversely affecting methylation reactions