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CircRHOT1 was found to promote the proliferation and migration of breast cancer cells and inhibit apoptosis and ferroptosis through the miR-106a-5p/STAT3 axis (Zhang et al., 2021b)
Thus, severe oxidative stress depletes cellular GSH [13] (Figure 2)
Statements Author contributions X-YL collected the related papers and was a major contribution in writing the manuscript
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Fourth, our focus on G-OSD constrains applicability to other dry-eye etiologies (e.g., postsurgical, autoimmune) and non-glaucomatous populations
