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VMAT2 mediates the sequestration of monoamine neurotransmitters, including dopamine and norepinephrine (NE), into synaptic vesicles

Therefore, nitric oxide synthase inhibitors being developed for acute diseases may also be suitable to treat COPD

Sci Rep 13(1):19862

& Lorenzon, G

In order to mitigate the adverse effects of mercury, strategies to overcome mercury toxicity are recommended

While the canonical IL-4/STAT6 pathway is the well-established initiator of the M2 transcriptional program, our findings suggest that direct activation of PKA in M1 macrophages (using Db-cAMP) was sufficient to significantly enhance efferocytosis