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Metabolite ratios have been successfully used in newborn screening for inherited metabolic disorders such as phenylketonuria, maple syrup urine disease, and certain disorders of organic acid or of mitochondrial fatty acid metabolism (35, 36) as well as in identifying metabolic underpinnings of more complex, multifactorial biological processes (37, 38)
Joo Roberto Resende Fernandes (CRM-SP 203006/RQE 91325), mdico do Pronto Atendimento e Corpo Clnico, especialista em Clnica Mdica do Hospital Israelita Albert Einstein
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Mol Pharmacol 2006;70:1602-11
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