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If your levels don't improve upon supplementation, investigate underlying GI conditions and medication interactions that could impair absorption

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Andrographolide suppresses NLRP3 inflammasome activation in microglia through induction of parkin-mediated mitophagy in in-vitro and in-vivo models of Parkinson disease

This inflammatory response may initially exert a neuroprotective effect by promoting the repair of damaged tissue and the elimination of cellular debris, while sustained inflammation may exert a negative effect by inhibiting the regeneration of neuronal tissue (Kempuraj et al., 2016

Jadhav PR, Goyal S, Sheetal GD, Dhavalshankh A, Dhavalshankh G (2024) Comparative evaluation of liver function test in refractive psoriasis patients treated with tofacitinib and apremilast