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Instruments were controlled via XCalibur 4.1 and data was analyzed on Tracefinder 5.1 using a 5ppm window from the predominant ion positive (carnitines) or negative (all other analytes)

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( A ) Plasma d 3 -TMAO concentrations in sequential venous blood draws after oral d 3 -l-carnitine challenge in vegans ( n = 7) and omnivores ( n = 8) at baseline, visit 1 (V1, 1 month), and visit 2 (V2, 23 months)

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