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Making natto includes a fermentation process to convert carbohydrates into alcohol or organic acids using microorganisms (natto starter/Bacillus subtilis natto) under anaerobic conditions

These encompass direct antioxidant therapies, such as SOD mimetics, Nrf2 activators, and mitochondria-targeted antioxidants, which directly neutralize ROS, as well as indirect antioxidant strategies, such as exercise therapy and phototherapy, which serve as potent modulators of cellular redox homeostasis through modulating redox signaling pathways (Fig

Several cellular defense systems, such as enzymes that remove oxidants or oxidant scavengers, balance the formation and the reactions of these intermediates

[28] Clements WT, et al

By prioritizing interdisciplinary collaboration and innovative research, AgNPs may emerge as a versatile and effective component of future cancer treatment paradigms, addressing unmet needs in precision oncology

The Nrf2/HO-1 pathway plays a critical role in cellular defense against oxidative stress (41)