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This imbalance of antioxidants in TED patients is due to the growth of orbital fibroblasts, synthesis of autoantibodies, degradation of preadipocytes to adipocytes, and secretion of endogenous cytokines (TNF, IL1-, and IFN), which consequently leads to fibro-adipose tissue development and inflammation of the extraocular muscle

Huang SH, Cao XJ, Liu W, Shi XY, Wei W

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In inhaled delivery applications, PEG lipids may undergo size changes and aggregation upon nebulization 177 , and their effects on lipid hydration and membrane structure warrant consideration 178

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