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Nomenclature and abbreviations CA - Cornu ammonis, CGN - Cerebellar granule neurons, CGP - Cerebellar granule precursor, CNS - Central nervous system, CSF - Cerebrospinal fluid, DG - dentate gyrus, ESC - Embryonic Stem Cell, GH - Growth hormone, IIS - Insulin/Igf-signalling, Igf - Insulin like growth factor 1, Igfbp - Insulin like growth factor binding protein, Ir - Insulin receptor, mTOR - mammalian target of rapamycin, NSC - Neural Stem Cell, NPC - Neural Progenitor cell, OB - Olfactory Bulb, OBSC - Olfactory Bulb stem cell, p - phospho-, SGZ - Subgranular zone, SVZ - Subventricular zone, TF - Transcription factor

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L., et al., Identification of Novel Risk Loci, Causal Insights, and Heritable Risk for Parkinson's disease: A Metaanalysis of Genomewide Association Studies, Lancet Neurology 18, no

They act as signaling molecules, hormones, and regulators that help coordinate processes such as metabolism, tissue repair, and hormone production

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It has been found that mutation in ZnT8 may contribute to dysregulation in insulin in the first passage through the liver and increase risk of type 2 diabetes mellitus development [136]