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The reasons for this gender disparity are not yet fully understood, but several factors have been proposed to contribute to this phenomenon 23

It is essential for target-directed degradation of miR-7 in cells, as measured using a reporter assay that provides a fluorescent readout of cellular miR-7 activity 10 after rescue of ZSWIM8 -knockout cells with a wild-type (WT) or variant ZSWIM8 transgene of interest (Extended Data Fig

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[DOI] [PubMed] [Google Scholar] 22.Schieber M., Chandel N.S