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Arginine deprivation by arginine deiminase of Streptococcus pyogenes controls primary glioblastoma growth in vitro and in vivo

T., Wu, S

Accordingly, novel technologies such as liquid biopsy, high-dimensional cytology, single-cell omics, metabolomics, and high-resolution imaging could be used to discover more easily detected biomarkers, bringing great convenience to drug-resistant cancer treatment

In: Patel V.B., editor

Thus, various tumors, including glioma, secondary glioblastoma, and acute myeloid leukemia (AML), harboring heterozygous point mutations in the active sites of IDH1/2 show dramatic increases in the R-2-HG levels 111,113,114,115