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Triglyceride-rich Lipoprotein Modulates Endothelial Vascular Cell Adhesion Molecule (VCAM)-1 Expression via Differential Regulation of Endoplasmic Reticulum Stress

The aim of this chemical selection was to identify chemicals with highest relevance towards the perturbation of initiation and promotion of human adipogenesis, and for a candidate test method to ideally capture both, the commitment of precursor cells such as MSCs, to the (WAT) adipocyte lineage, and the subsequent promotion of intracellular lipid accumulation

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Acknowledgements Projects in the M.W

It is an effective TG-reducing agent and remains the only lipid modifying drug to date that reduces cardiovascular mortality over and above statin therapy