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Demonstration that improving the biophysical properties of an antibody (bococizumab) correlates with a reduced immunogenicity risk in nonclinical assays

Furthermore, in 100 PD and 50 normal subject, significant increases were noticed in the concentrations of ornithine, phenylalanine, isoleucine, -hydroxybutyric acid, tyrosine, and succinic acid detected by high-resolution nuclear magnetic resonance spectroscopy (Wang et al., 2023) (see Table 4) Table 4 Urine biomarkers in PD patients

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G protein-coupled receptor systems and their lipid environment in health disorders during aging
