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2023 Aug 6;14(13):2481-2490

However, while early indications are promising, clinical trials and long-term studies are required to confirm the safety and effectiveness of this combination

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The structural modification substituting a hydroxyl group where MT-II carries an amide was designed during Palatin Technologies' development program to concentrate therapeutic effects at MC3R and MC4R while stripping out the tanning and dermatological risk that come with strong MC1R agonism

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If you are using this blend and feeling good about your results, there is no compelling reason to switch away from it