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The human body does not metabolize PFAS, leading to its excretion without any metabolic transformations (13, 22)
D.TiribelliC.Ghersi-EgeaJ
Of importance, the -ketoglutarate dehydrogenase (KGDHC) and pyruvate dehydrogenase (PDC) complexes produce ROS as a result of both forward electron transfer and RET

Since 1990, significant advances have been made in phosphor- and phosphon-amidate analogs, and it is important to note the only US FDA-approved phosphonate prodrug since 2007, tenofovir alafenamide, includes an amidate moiety [1,81]

CRC Taylor and Francis Group, Boca Raton, pp 71103 Board PG, Menon D (2013) Glutathione transferases, regulators of cellular metabolism and physiology
In the in vivo experiments, the proportion of M1 macrophages was reduced both two and four weeks after surgery at the tendon-bone interface
