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2019;8(10):e1072672

Mitochondrial respiratory chain complex activity assay The mitochondrial complex spectrophotometric assays were carried out using published protocols 58,59

Common histone modifications [edit] The four common histone modifications and their respective writer and eraser enzymes are shown in the table below

Further exploration revealed that this was driven mainly by the difference between patients with ME/CFS and HCs (F = 9.589, p = 0.004), with ME/CFS patients showing higher lactate levels than controls, although a trend towards significant difference between patients with ME/CFS and long COVID was also noted (F = 4.031, p = 0.052)

Putnam JB JR, Correa A, Swisher SG, Smythe WR, Rice DC , Roth JA, Vaporciyan AA, Walsh GL

The observed benefits suggest that CA could play a significant role in mitigating the damage associated with CIRI by addressing various pathological mechanisms involved in the injury process
