local glutathione reperfusion Frontiers Ischemia Reperfusion Research | BMG
Description
Endocrinology 159(11):38013812
doi: 10.1089/acm.2020.0292
doi: 10.1136/jcp.2006.038976 115 ShinVYWuWKChuKMWongHPLamEKTaiEKet al
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Prolonged ER stress and activation of the unfolded protein response (UPR) contribute to macrophage apoptosis as substantiated by studies showing that apoptosis and the UPR effector, CHOP, increase with each stage of atherosclerosis in humans, but the largest increase is observed in the vulnerable plaque (175)
The detailed workflow is shown in Fig
