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However, when the cell detects an apoptotic stimulus, such as DNA damage or metabolic stress, the intrinsic apoptotic pathway is triggered and mitochondrial cytochrome c is released into the cytosol (Kroemer et al., 2007)
The risk of asthma is higher in children exposed to acetaminophen during pregnancy, and that risk is exacerbated by maternal genetic variants related to acetaminophen detoxification.[ref] Genetic interactions with acetaminophen: With multiple routes of detoxification, most people can take acetaminophen without liver damage
doi: 10.1186/1550-2783-4-12 23 FinkJSchoenfeldBJHackneyACMatsumotoMMaekawaTNakazatoKet al
Laing S, Bielfeldt S, Ehrenberg C, et al
