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doi:10.1007/s10863-009-9257-z pmid:19967436 Hatzoglou A, Kampa M, Kogia C, Charalampopoulos I, Theodoropoulos PA, Anezinis P, Dambaki C, Papakonstanti EA, Stathopoulos EN, Stournaras C, Gravanis A, Castanas E (2005) Membrane androgen receptor activation induces apoptotic regression of human prostate cancer cells in vitro and in vivo

Pain Processing Mechanisms Central Sensitization (via mGlu2 receptor upregulation)[4][5] Neuroinflammation (modulates glial activation)[12][13] Mitochondrial Dysfunction (enhances ATP production, -oxidation)[2][13] Oxidative Stress (direct antioxidant activity)[2][13] Systemic Inflammation limited direct evidence SUMMARY OVERVIEW CLINICAL PEARLS 1