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419 In a 12-week comparison trial in 57 patients with mild-to-moderate depression, a dose-escalation of rhodiola extract (ranging from 3401,360 mg daily) led to slightly lower likelihood of improvement than sertraline, relative to placebo, but caused fewer adverse side effects

as well as the differences in cis -sabinene hydrate, germacrene-D, dill apiol, t -cadinol, SH, and OS were non significant

Kidd 1997)

These TAMs further suppress antitumor immune responses and contribute to the establishment of an immunosuppressive TME

McKnight, K

238 However, other works have demonstrated that SIRT2 promotes cancer growth by stabilizing the Myc family of oncoproteins 239,240 and enhancing the signaling of the Notch pathway