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The VDAC3/DHODH axis ameliorates sepsis-induced myocardial injury by regulating ferroptosis

Quality control (QC) samples were prepared by pooling aliquots of study samples and injected after every four study samples to monitor instrument performance throughout these analyses

Pearson, Isabel Gonzlez-Mariscal, Gabriel Olveira, Francisco-Javier Bermu Biomedicine & Pharmacotherapy.2024

doi: 10.7759/cureus.68063 140 NeogMKRasoolM

After SCI, a large number of neural cells die and axons break, leading to functional impairment

We do not exclude the potential contribution of non-canonical ferroptosis regulatory pathways, such as the FSP1-CoQ10-NAD(P)H system, the GCH1-BH4-DHFR axis, mitochondrial DHODH activity, non-classical roles of p53, or alterations in autophagy-mediated iron and lipid handling
