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This shows that in PTSD patients, oxidative stress not only changes the activation pattern of the HPA axis, but may also interrupt adrenal gland function, further stimulating a vicious cycle of stress responses
& Landman, B
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Treated mice show preservation of striatal dopamine levels and TH-positive neuron counts in the substantia nigra compared to untreated toxin-lesioned controls (45)

The latter process occurs partly by a passive process of carrier-mediated diffusion and partly by mediation by organic anion transporter proteins
Olsson U