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The vestibule exhibits low drug permeability because of the keratinized squamous epithelium

Moreover, ILDR enhances the efficacy of ICI through microbiota- and BA-mediated mechanisms, including increased DC activation and CD8+ T cell recruitment, potentially driven by DCA enrichment (60)

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Glutathione is considered the most important antioxidant because it is the only one capable of working with enzymes

Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target

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