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Figure 8 Statements Data availability statement The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation

While synthesis and regeneration have been well characterized, GSH degradation remained less clear

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FA cells detect the lack of ironsulfur cluster biosynthesis as a deficit in iron availability, leading to the upregulation of iron import proteins such as TfR and the downregulation of the only known iron exporter, Fpn, to increase intracellular iron levels