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doi: 10.18632/oncotarget.9962 73 BachDHKimDBaeSYKimWKHongJYLeeHJet al

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For each plate, the concentration of product was normalized by assigning a score of 0 (0%) to the negative control (average of maximal concentration of product measured in the presence of enzyme without any inhibitor) and a score of 1 (100%) was assigned to the positive control (average minimal concentration of product measured in the presence of enzyme with the reference inhibitor, i.e., EA)